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Neo-Advent Technologies, LLC (NAT) is a pre-clinical contract research organization offering a full spectrum of CMC capabilities required for the successful advancement of its clients' drug development programs. Core competencies include Drug Formulation and Analysis.

The company operates state-of-the-art Solid Dose facility to support accelerated development of the tablet forms and coated formulations, from feasibility studies to production batches. NAT provides comprehensive analysis, conducts due diligence, and designs IP strategies to enable launch of programs focused on new drug delivery approaches including drug reformulation.

Drug Formulation
We provide an expertise in drug formulation, from concept design to cGMP technology transfer, including solid dosage forms, topical, ocular, and parenteral compositions.
API Micronization
NAT will help to micronize your API using either wet or dry milling. We offer several streamlined approaches including a uniquely suited for early stage pre-clinical development Micronization XPRESS - a 7-day accelerated program to rapidly micronize an API for increased solubility and bioavailability that features an unparalleled speed, delivery of a ready-for-testing formulation for in vivo studies, small amount of the API required for the study, as well as stability control.
Drug Delivery
The Company has developed particular expertise in several specialized areas of controlled drug release and delivery including sol-gel nanoencapsulation, smart hydrogels and biomaterials, electroreologically-controlled drug release, and compositions based on polyphosphazene polymers.
Analytical and Bioanalytical
Our analytical and bioanalytical services span from the HPLC method development to thermal analysis, TGA, DSC, and particle size analysis to metabolite characterization and profiling by LC/MS. We conduct a full range of the GLP stability studies and thoroughly analyze polymers and raw ingredients using the extensive Instrumentation Suite.
Custom Synthesis
NAT operates a fully equipped synthetic scale-up facility (5-50L reactors, Load&Lock purification columns) and carries out work on synthetic optimization of drug candidates and intermediates, as well as polymer building blocks. We also offer a selection of chiral amino acids, biopolymers, polymer building blocks (Monomers For High Performance Polymers), polyphosphazene polymers, porphyrins, and other custom items from our Catalog of Chemical Reagents and Materials.
Pharmacology and Toxicology
We offer a variety of services in the areas of toxicology and pharmacology to assist companies in the preclinical and clinical development of pharmaceuticals and medical devices. Evaluation of in-licensing and out-licensing opportunities include safety assessment of small molecules and biopharmaceuticals, drug metabolism and pharmacokinetics, and biocompatibility analysis for medical devices.
Regulatory Support for Drugs and Medical Devices
We design comprehensive regulatory strategies for preclinical and early clinical development and provide assistance in interactions with FDA and preparing IND filing.
Material Science
NAT develop high performance coatings that are based on the hybrid organic-inorganic sol-gel scaffolds and conduct research and development work in light-weight structural materials and laminates.


Drug Formulation Brochure
Sample Submission Form
Reagents Catalogue